Louis’ Review on Glioblastoma Standard of Care is Published!
Glioblastoma is the most common and aggressive brain tumor in adults. Despite surgery, radiation, and chemotherapy, survival rates remain low, which emphasizes the urgent need for improved therapies. Current preclinical models use untreated tumors, which do not reflect the clinical scenario where patients already receive initial treatments. This review examines the effects of current treatments […]
Louis’ New Paper on Luciferase-Expressing Mouse Glioblastoma Models Published!
Inconsistent engraftment of luciferase-expressing tumors, especially GL261 Red-FLuc, has been reported in the recent literature. However, techniques to improve tumor take have not been described. Our study aimed to optimize two luciferase-expressing mouse glioblastoma models, GL261 Red-FLuc and TRP-mCherry-FLuc, which revealed differences in tumor development and characteristics. Congratulations Louis! View Publication
Graduation Party!
We celebrated Louis for completing his PhD, Tiffany for completing her PharmD/MS, and Jason for completing his MD. We are very proud of you and wish you the best of luck in your future endeavors!
UK COP Graduation: Congratulations, Louis
Louis received his Doctor of Philosophy in Pharmaceutical Sciences. Bjoern hooded Louis during the official UK College of Pharmacy Graduation Recognition Ceremony. Congratulations, Louis!
UK COP Graduation: Congratulations, Tiffany
Tiffany received her Doctor of Pharmacy and her Master in Pharmaceutical Sciences. The University of Kentucky College of Pharmacy’s 2024 Graduation Recognition Ceremony took place in the Singletary Center for the Arts. Tiffany was one of 9 Master of Science/PharmD Recipients. Congratulations, Tiffany!
Louis received PhD in Pharmaceutical Sciences
Louis successfully defended his PhD research entitled “Inhibiting PI3K/Akt to Enhance Brain Uptake of Anticancer Agents in Glioblastoma.” Louis joined the BHL in 2019 as an MD/PhD student studying the overexpression of drug-efflux pumps in glioblastoma and the development of a novel therapeutic strategy to increase brain uptake of anticancer drugs. Louis will now continue […]
Tiffany Successfully Defended Her MSPS
Tiffany joined the BHL in May 2021 as a Master’s student in Pharmaceutical Sciences to work on the role of NOX2 as a new drug target in Alzheimer’s disease to repair blood-brain barrier dysfunction. Tiffany successfully defended and will graduate with a dual PharmD/MS degree on May 3. Congratulations, Tiffany!
Geetika’s paper on “Cognitive decline, Aβ pathology, and blood-brain barrier function in aged 5xFAD mice” accepted by FBCNS
Alzheimer’s disease patients develop blood-brain barrier dysfunction to varying degrees. How aging impacts Aβ pathology, blood-brain barrier function, and cognitive decline remains largely unknown. In this study, we used 5xFAD mice to investigate changes in Aβ levels, barrier function, and cognitive decline over time. Congratulations on your first author publication, Geetika!
Professor Ute Hellmich visits BHL
Ute Hellmich, Professor for Biostructural Interactions at the Faculty of Chemistry and Earth Sciences, Institute of Organic Chemistry and Macromolecular Chemistry, and Cluster of Excellence Balance of the Microverse at Friedrich Schiller University Jena in Germany, visited the BHL. We had a lively mentoring lunch with Dr. Hellmich, during which she talked about long hours […]
Jasmine and Yingying inducted into the Rho Chi Pharmacy Honor Society
Jasmine and Yingying were invited to join the UK Rho Chi Pharmacy Honor Society. Rho Chi is an international honor society that recognizes academic excellence in pharmacy. The society promotes pharmaceutical sciences and encourages fellowship and high scholastic achievement among pharmacy students. As a Rho Chi faculty member, Bjoern welcomed Jasmine and Yingying to the […]