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Velmurugan GV, Vekaria HJ, Hartz AMS, Bauer B, Hubbard WB
2024 21:81, https://doi.org/10.1186/s12987-024-00579-9
Neurovascular deficits and blood-brain barrier (BBB) dysfunction are major hallmarks of brain traumaand neurodegenerative diseases. Oxidative stress is a prominent contributor to neurovascular unit (NVU) dysfunction and can propagate BBB disruption. Oxidative damage results in
Rodgers LT, Villano JL, Hartz AMS, Bauer B
2024, 16, 2638. https://doi.org/10.3390/cancers16152638
Rodgers LT, Schulz Pauly JA, Maloney BJ, Hartz AMS, Bauer B
2024, 16, 1997. https://doi.org/10.3390/ cancers16111997
Glioblastoma (GBM) is the most aggressive brain cancer. To model GBM in research,orthotopic brain tumor models, including syngeneic models like GL261 and genetically engineeredmouse models like TRP, are used. In longitudinal studies, tumor growth and