Neurovascular deficits and blood-brain barrier (BBB) dysfunction are major hallmarks of brain trauma and neurodegenerative diseases. Oxidative stress is a prominent contributor to neurovascular unit (NVU) dysfunction and can propagate BBB disruption. Oxidative damage results in an imbalance of mitochondrial homeostasis, which can further drive functional impairment of brain capillaries. To this end, we developed a method to track mitochondrial-related changes after oxidative stress in the context of neurovascular pathophysiology as a critical endophenotype of neurodegenerative diseases.
Pannita achieves a perfect Bradford assay
Congratulations to Pannita on a perfect Bradford protein assay! This is a rare accomplishment, with only a few BHL members having achieved it over the years. Following a long-standing lab tradition, we celebrated Pannita’s perfect Bradford with a pizza party.
October 19, 2026
