Oxidative stress contributes to blood–brain barrier leakage, renal dysfunction, and cognitive decline in Alzheimer’s disease. In this study, the team used 5xFAD mice to show that N-acetylcysteine (NAC) reduces Aβ-induced oxidative damage and improves cognition and organ function. Congratulations Atcharaporn and team!

Hady presents at the Trainee Research Day
Hady presented a poster on anti-amyloid antibodies and their effects on blood-brain barrier integrity at the College of Medicine Trainee Research Day. This work represents a new and timely research direction in the lab that aligns with the development of novel disease-modifying antibody therapeutics for Alzheimer’s disease.


