Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up
Brain cancer is a devastating disease. Despite extensive research, treatment of brain tumors has been largely ineffective and the diagnosis of brain cancer remains uniformly fatal. Failure of brain cancer treatment may be in part due to limitations in drug delivery, influenced by the ABC drug efflux transporters P-glycoprotein (P-gp) and breast cancer resistance protein […]