Glioblastoma Standard of Care: Effects on Tumor Evolution and Reverse Translation in Preclinical Models
Optimization, Characterization, and Comparison of Two Luciferase-Expressing Mouse Glioblastoma Models
Glioblastoma (GBM) is the most aggressive brain cancer. To model GBM in research,orthotopic brain tumor models, including syngeneic models like GL261 and genetically engineeredmouse models like TRP, are used. In longitudinal studies, tumor growth and the treatment responseare typically tracked with in vivo imaging, including bioluminescence imaging (BLI), which is quick,cost-effective, and easily quantifiable. However, […]