New Paper Published:  Synergistic Effects of Plasma S100B and MRI Measures of Cerebrovascular Disease on Cognition in Older Adults

Our collaborative work with Dr. Gold and his team underscores the potential of combining blood biomarkers and brain imaging to identify early signs of vascular contributions to cognitive decline. By measuring levels of S100b, an indirect marker of blood-brain barrier leakage, and pairing it with advanced neuroimaging, we identified patterns associated with memory loss in older adults. The findings underscore how a multimodal approach can better predict who’s at risk for vascular cognitive impairment and dementia (VCID).

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Recent Posts

Hady presents at the Trainee Research Day

Hady presented a poster on anti-amyloid antibodies and their effects on blood-brain barrier integrity at the College of Medicine Trainee Research Day. This work represents a new and timely research direction in the lab that aligns with the development of novel disease-modifying antibody therapeutics for Alzheimer’s disease.

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BHL Team takes the Lexington Polar Plunge

We participated in the Polar Plunge to support Special Olympics Kentucky. Despite the cold conditions (outside temperature: 12°F; water temperature: 30°F), we joined other community participants to help raise funds and awareness for athletes with intellectual disabilities. The event provided an opportunity for the lab to contribute to a local

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BHL Holiday Party

The BHL Annual Holiday Party brought the team together to mark the end of the year. We shared food, spent time together, and played a white elephant gift exchange. It was a nice opportunity to connect outside the lab!

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